Research Associate

Overview

Integrated Resources, Inc (IRI) is seeking a Research Associate based in Lexington, MA, for a 12-month contract position. The role involves providing technical research support across multiple projects aimed at accelerating the evaluation and clinical development of therapeutic candidates.

Key Responsibilities

• Conduct siRNA drug candidate screening, identifying hits and optimizing leads.
• Utilize cellular and molecular biology techniques such as mammalian cell culture, in vitro screening, cell-based assays, RNA extraction, and quantitative real-time PCR (RT-qPCR).
• Interpret and present experimental data during team meetings.
• Maintain precise and comprehensive laboratory records.
• Prepare Standard Operating Procedures (SOPs) and technical documentation as required.
• Work collaboratively with research colleagues to rapidly resolve critical drug efficacy questions.
• Review and analyze scientific literature to inform research strategies, primarily contributing through hands-on laboratory work.

Required Qualifications

• Master's degree in Cell and Molecular Biology, Pharmaceutical Sciences, or related discipline.
• Over four years of relevant laboratory experience in drug discovery within academic or industrial settings.
• Proficient in cellular and molecular biology methods including mammalian cell culture, cell-based assays, and RT-qPCR.
• Experience culturing primary human adipocytes and hepatocytes is advantageous.
• Familiarity with advanced in vitro model systems such as organoids and 3D culture platforms is highly desirable.
• Practical knowledge of RNA interference (RNAi) techniques and in vitro screening preferred.

Additional Information

Contract Length: 12 months
Work Location: Onsite at Lexington, Massachusetts